Research and Publications

Field of Research

Our department is pursuingresearch work in the following areas:

1.      NaturalProduct Biomolecule Analysis

2.      Haemoglobinopathies

3.      GenomicAnalysis for Various Diseases

4.      PlantTissue Culture

5.      ScientificValidation of Traditional Knowledge

6.      EnvironmentalAssessment of Heavy Metals and Their Health Hazard Impacts

7.      PharmacologicalStudy of Medicinal Plants for Various Diseases

8.      ChemokineReceptors and Their Role in Various Diseases

Research Laboratories / Cells

To support the above research areas, the department operatesthe following laboratories and cells:

1.     Molecular Biology Laboratory

2.     Genomics Laboratory

3.     Traditional Knowledge Validation Laboratory

4.     Tissue Culture Laboratory

5.     Sickle Cell Unit

6.     Instrumentation Cell

7.     Sterilization Cell

Running Projects

Completed Projects

1.     Mosquito Fecundity& Malarial Infestation in Dantewada (Bastar) — DBT Govt. of India; Budget:₹8,00,000; Mentor: Dr. Anil Kumar; Ref: BT/IN/INDO-US/Foldscope/39/2015, 2018;Status: Completed.

2.     ErythrocyteDisorders Among SC/ST Population of Kabirdham District — DST; Budget:₹20,00,000; PI: Dr. Anil Kumar; Ref: NRDMS/01/23/026, June 27, 2016; Status:Completed.

3.     Association ofOral Cancer with CYP1A1 & GSTM1 Genotypes in Chhattisgarh Population —Dept. of Health Research; Budget: ₹28,38,000; PI: Dr. Madhu Pandey; Mentor: Dr.Anil Kumar; Ref: DHR/HRD/LTF1-02-2015-16, Feb 2016; Status: Completed.

4.     Prevalence ofHuman Parvovirus B19 in Sickle Cell Anemia Tribal Population — DST; Budget:₹17,44,000; Woman Scientist A: Dr. Seema Tripathi; Mentor: Dr. Anil Kumar; Ref:DST/Disha/SoRF-PM/023/2013, 2014; Status: Completed.

5.     GeneticPolymorphism of Chemokine Receptors for HIV-1 Infection in Tribal Population —DST; Budget: ₹3,25,600; Woman Scientist B: Ms. Swati Pandey; Mentor: Dr. AnilKumar; Ref: NASI/SoRF-I/2014-15/38, 2014; Status: Completed.

6.     Evaluation ofAntioxidant Properties of Medicinal Plants on Lymphocytes of Oryctolaguscuniculus — CCOST; Budget: ₹5,00,000; PI: Dr. Anil Kumar; Ref:2154/CCOST/MRP/2013, 2013; Status: Completed.

7.     Isolation &Characterization of Biomolecules from Native Plants of Chhattisgarh — CG StateMedicinal Plant Board (AYUSH); Budget: ₹1,30,44,000; PI: Dr. Anil Kumar; Ref:Res/1051, 2010; Status: Completed.

8.     Study of SickleCell Hemoglobinopathies in Chhattisgarh — UGC New Delhi; Budget: ₹10,00,000; PI:Dr. Anil Kumar; Ref: F.No. 32-s493/2006 (SR), 2007; Status: Completed.

9.     Study of SickleCell Disease and its genetic flow in Rajnandgaon & Durg districts — DSTGovt. of India; Budget: ₹10,00,000; Woman Scientist: Seema Tripathi; Mentor:Dr. Anil Kumar; Ref: SSD/SS/025/2006, 2007; Status: Completed

Publication

Sahu,M., Kumar, D., Kumar, S., & Kumar, A. (2025). The prevalence of chemokinereceptors (CCR5-Δ32, CCR5-m303, CCR2-64I, and SDF1-3'A) in the population withsickle cell anemia. Gene Reports, 102261.

Kumar,D., Kumar, S., Sahu, M., Pender, G. C., Govindasamy, C., Kumar, S., &Kumar, A. (2025). GC-MS identified bioactive compounds of Urena lobata L.demonstrate anti–inflammatory and immunomodulatory potentials againstrheumatoid arthritis: An in silico, in vitro and in vivo evaluation. Pharmacological Research-Natural Products, 6, 100152.

Kumar,D., Kumar, S., Sahu, M., Govindasamy, C., & Kumar, A. (2024). Trachelogeninfrom Urena lobata demonstrates promising potentials against SARS-CoV-2 Mpro(3CL Protease) of Endemic COVID. Journal of King Saud University-Science, 36(11), 103572.

Kumar,S., Kumar, D., Sahu, M., Maurya, N. S., Mani, A., Govindasamy, C., & Kumar,A. (2024). An in vitro and in silico antidiabetic approach of GC–MS detectedfriedelin of Bridelia retusa. Journal of King Saud University-Science, 36(10), 103411.

Kumar,A. (2024). Machine learning for Markov modeling of COVID-19 dynamics concerningair quality index, PM-2.5, NO2, PM-10, and O3. Journal homepage: http://iieta. org/journals/ijcmem, 12(2), 121-134.

Mishra,N., Tripathi, S., Nahar, L., Sarker, S. D., & Kumar, A. (2024). Mitigationof arsenic poisoning induced oxidative stress and genotoxicity by Ocimumgratissimum L. Toxicon, 238, 107603.

Singh,E., Shivwanshi, L. R., & Kumar, A. (2024). A positive correlation betweenmutated gene of sickle cell anemia and glucose-6-phosphate dehydrogenase amonggond tribes of Chhattisgarh, India. Mutation Research-Fundamental and Molecular Mechanisms ofMutagenesis, 828, 111849.

Zeb,A., Khan, I. U., Tripathi, S., Sahu, M. R., & Kumar, A. (2023). AnInappropriate Rise in NO2 During the COVID-19 Pandemic in the Urban Area ofChhattisgarh, India. Nature Environment and Pollution Technology, 22(2), 671-680.

Kumar,A., Kumar, S., & Jain, N. (2023). Impact of Increasing Climatic Temperatureon Crop Yield. Mol. Biol. Plant Physiol, 33(3).

Singhal, S., Bhadana, R., Jain,B. P., Gautam, A., Pandey, S., & Rani, V. (2024). Role of gut microbiota intumorigenesis and antitumoral therapies: an updated review. Biotechnology andGenetic Engineering Reviews, 40(4), 3716–3742.https://doi.org/10.1080/02648725.2023.2166268

COLLABORATIONS